Editorial policy
Commercial disclosure
Canine Peptide Guide is supported by Pet & Peps Research, which sells research peptides. We may earn revenue when readers follow links to their store. Every such link is marked as sponsored.
That relationship does not determine how compounds are graded. The evidence grades on this site reflect what the published literature supports, and several compounds Pet & Peps Research sells carry the lowest grade we award, prominent contraindications, or an explicit statement that no canine data exists. A guide that graded everything favourably would be worthless to the reader and, in the longer run, to the sponsor.
How content is researched
Every factual claim traces to a cited primary source. We currently cite 32 peer-reviewed studies, of which 6 were conducted in dogs. Where a claim rests on rodent, equine, in vitro or human data extrapolated to dogs, we say so rather than presenting it as canine evidence.
Dosing figures are reported as they appear in the source literature. They are not recommendations, and we do not adjust or average them to produce a tidier number. Where the literature reports a wide range, we show the range.
The evidence grading system
Three grades. Good evidence means multiple studies in the target species or regulatory approval in two or more countries. Emerging means some published data supports the use but it may rest on a single study or on extrapolation. Preliminary means cell culture, rodent models, or mechanism alone, with no companion animal data.
These grades describe the strength of published evidence, not our opinion about whether a compound works. A compound can be genuinely promising and still be graded preliminary, because the grade is about what has been demonstrated rather than what might be true.
What we will not publish
- Fabricated citations. Where we cannot find a source for a claim, the claim does not appear.
- Efficacy claims that outrun the evidence. Language on this site is deliberately cautious — "investigated for", "reported to", "associated with" — because that is what the underlying literature supports.
- Contraindications buried below the fold. Where a compound carries a serious risk, it appears near the top of the page.
Corrections
If you find an error — a misread study, a dosing figure that does not match its source, a citation that does not say what we claim it says — we want to know and will correct it. Accuracy is the only durable asset a reference site has.
Authorship and review
Content is compiled and reviewed by the Canine Peptide Guide Editorial Team. Content on this site is compiled from peer-reviewed primary literature and reviewed for accuracy against the cited sources before publication.
We are actively seeking a licensed veterinarian to serve as named clinical reviewer. Until that is in place, readers should weigh this site as what it is: a careful synthesis of published literature, not a clinical opinion.
What this site is not
This is not veterinary medical advice and does not establish a veterinarian-client-patient relationship. Most compounds described here are investigational or used off-label and are not FDA-approved for these purposes in dogs. Extralabel drug use in animals requires a valid VCPR and the direct supervision of a licensed veterinarian under AMDUCA (21 U.S.C. §360b).